Biotin and derivatives
Medchemexpress LLC DOTA-NHS-ester | 170908-81-3 | >97.0% | 501.49 g/mol | C20H31N5O10 | 250 MG
DOTA-NHS-ester is an NHS-activated DOTA chelator used to conjugate the DOTA moiety to biomolecules (for example, peptides, proteins, and affibodies) to enable radiolabeling for PET, SPECT, and radiotherapeutic research. It is supplied as a white to off-white solid with high purity and is soluble in DMSO.
- NHS-activated DOTA chelator for amine conjugation.
- High purity (>97.0%).
- Molecular weight 501.49 g/mol; formula C20H31N5O10.
- Soluble in DMSO (50 mg/mL); ultrasonic assistance recommended.
- Storage: sealed, away from moisture; in solvent -80°C (6 months) or -20°C (1 month).
- Intended for radiolabeling research (PET/SPECT); not for human use.
Chem-Impex International, Inc. (+) Biotinyl-6-aminohexanoic acid | 72040-64-3 | MFCD00144853 | 250MG
(+) Biotinyl-6-aminohexanoic acid, 72040-64-3, MFCD00144853, 250MG
Medchemexpress LLC Biotin-PEG3-acid 100mg | 252881-76-8 | 100 MG
Biotin-PEG3-acid is a biotin-labeled polyethylene glycol (PEG3) linker containing a terminal carboxylic acid. It is supplied as a purified research-grade small molecule for use in PROTAC synthesis and biotinylation applications.
- Biotin-labeled PEG3 linker with terminal carboxylic acid.
- Designed for PROTAC synthesis and biotinylation workflows.
- High purity, 98.0%.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Store sealed at 4°C; in solution store at -80°C for long-term stability.
- Available in 100 MG and larger pack sizes for research use.
Medchemexpress LLC Biotin-DADOO TFA | 194920-57-5 | 95.0% | 250 MG
Biotin-DADOO TFA is a biotinylating reagent that is conjugated to CMC thiosulfate.
- Can be utilized to synthesize biotin-estradiol conjugates.
- Used for the determination of plasma estradiol concentrations by enzyme immunoassay.
- Appearance: oil.
- Color: light yellow to brown.
- For research use only.
Medchemexpress LLC Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine) | 138529-46-1 | 98.0% | 500 MG
Biotin-DADOO is a biotin-containing amine compound and a biotinylation reagent. It acts as an amino component in the nucleophilic ring-opening reaction of epoxidized ω-double bonds during the synthesis of biotinylated inhibitor derivatives. This product can be conjugated with carboxymethyl cellulose derivatives and is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays. It can also be utilized in influenza A research.
- Captures free influenza neuraminidase on streptavidin-coated polystyrene plates.
- Forms stable self-assembled monolayers (SAMs) on planar gold surfaces.
- Forms a stable biotin-estradiol conjugate.
Medchemexpress LLC Mal-GGG-Bal-NHS ester | 1193111-65-7 | 97.6% | 522.47 g/mol | 5 MG
Mal-GGG-Bal-NHS ester is an ADC linker reagent used to introduce a maleimide-containing GGG-Bal-NHS moiety for conjugation to antibodies or other amine- or thiol-containing biomolecules.
- Used as an ADC linker in antibody-drug conjugate synthesis.
- Contains an NHS ester for amine coupling and a maleimide for thiol conjugation.
- High reported purity of 97.6% for reliable coupling performance.
- Soluble in water at high concentration (50 mg/mL) with ultrasonic treatment if needed.
- Recommended storage under inert atmosphere and cold conditions to preserve stability.
Medchemexpress LLC FP-Biotin | 259270-28-5 | 99.1% | 592.75 | 1 MG
FP-biotin is a potent organophosphorus toxicant, ideal for identifying new biomarkers of organophosphorus toxicants exposure. It quantifies the activity of FAAH, ABHD6, and MAG-lipase. This product is utilized in plasma studies because biotinylated peptides can be easily purified by binding to immobilized avidin beads. It is suitable for identifying organophosphorus toxicants reactive proteins and is for research use only.
- Quantifies FAAH, ABHD6, and MAG-lipase activity
- Used in plasma studies for easy purification of biotinylated peptides
- Suitable for identifying organophosphorus toxicants reactive proteins
- Appears as a white to light yellow solid
- Ships at room temperature in continental US
- Store at -20°C under nitrogen; in solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
- Soluble in DMSO (25 mg/mL)
Medchemexpress LLC M-PEG11-NHS ester | 3119903-67-9 | MFCD28976661 | C28H51NO15 | 50 MG
m-PEG11-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. This mechanism leverages the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Molecular weight of 641.70
- Appears as a solid
- Used as a PROTAC linker for the synthesis of PROTACs in research settings
Medchemexpress LLC Biotin-PEG2-NH-Boc | 175885-18-4 | C21H38N4O6S | 50 MG
Biotin-PEG2-NH-Boc is a biotin-labeled, PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This linker is essential for constructing PROTAC molecules, which function by connecting an E3 ubiquitin ligase ligand to a target protein ligand, enabling the selective degradation of target proteins via the intracellular ubiquitin-proteasome system.
- Biotin-labeled for specific applications
- PEG-based linker for PROTAC synthesis
- Utilizes the ubiquitin-proteasome system for selective protein degradation
Medchemexpress LLC Biotin-PEG2-NHS ester | 596820-83-6 | 96.7% | C21H32N4O8S | 100 MG
Biotin-PEG2-NHS ester is a biotin-labeled, PEG-based PROTAC linker designed for research use. It can be utilized in the synthesis of PROTACs, which employ the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs consist of two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein.
- Biotin-labeled, PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC M-PEG14-NHS ester | 773.86 | 100 MG
M-PEG14-NHS ester is a solid laboratory chemical intended for research use only. It is stable under recommended storage conditions and is not classified as a hazardous substance or mixture. This product is suitable for the manufacture of substances and has not been validated for medical applications.
- Solid appearance
- Stable under recommended storage conditions
- Not classified as a hazardous substance or mixture
- For research use only
![Medchemexpress LLC 1H-thieno[3,4-d]imidazole-4-pentanamide, N-[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl] | 188682-72-6 | MFCD00213997 | 99.9% | 533.68 g·mol⁻¹ | C26H39N5O5S | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000288114.png-250.jpg)
Medchemexpress LLC 1H-thieno[3,4-d]imidazole-4-pentanamide, N-[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl] | 188682-72-6 | MFCD00213997 | 99.9% | 533.68 g·mol⁻¹ | C26H39N5O5S | 10 MG
Biotin-BMCC is a maleimide-activated biotinylation reagent that reacts selectively with free thiol groups of cysteines to install a biotin tag for detection, affinity capture, or purification of proteins and peptides.
- Reacts selectively with free thiol groups (cysteines).
- Introduces a biotin handle compatible with streptavidin/avidin affinity methods.
- High chemical purity (99.9%).
- Suitable for labeling proteins and peptides for detection and affinity purification.
Apexbio Technology LLC 5-Carboxyfluorescein diacetate N-succinimidyl ester 150206-05-6 5mg
5-Carboxyfluorescein diacetate N-succinimidyl ester (CAS 150206-05-6) is a fluorescent cell-permeable dye It is designed to enable stable cell labeling by facilitating intracellular conversion and covalent attachment to cellular amines 5-Carboxyfluorescein diacetate N-succinimidyl ester exerts its activity through membrane permeation intracellular esterase-mediated cleavage of acetate groups and subsequent covalent coupling to intracellular targets resulting in persistent fluorescence through cell division Based on these properties 5-Carboxyfluorescein diacetate N-succinimidyl ester holds research potential in tracking lymphocyte migration analyzing cell proliferation and investigating cell dynamics and interactions in various in vitro and in vivo experimental models
Medchemexpress LLC Azido-PEG9-NHS ester | 2801772-87-0 | 98.0% | C25H44N4O13 | 100 MG
Azido-PEG9-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It serves as a click chemistry reagent, featuring an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne-containing molecules. This ester can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Peg-based protac linker
- Used in the synthesis of protacs
- Functions as a click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions